Institut Pasteur is a non-profit private foundation which contributes to the prevention and treatment of disease, primarily infectious diseases, through research, education, and public health activities. With an independent international network of Pasteur institutes, which constitutes an original and autonomous body, the only one of its kind in the world. The research priorities are the fight against infectious disease, as well as certain types of cancer, genetic diseases, neurodegenerative diseases, and allergy. The main fields of research concern microbiology, immunology, molecular biology, neurobiology, genomics and post-genomics. Institut Pasteur has also a role in education for young scientists from all over the world, as well as public health activities.

Our objectives are: to identify H. pylori genes or allelic polymorphisms specifically associated with progression towards MALT lymphoma. Unique genes unique to a MALT lymphoma strain will be identified and evaluated as predictive markers of MALT lymphoma induction. to analyse the mutagenic effects of this H. pylori MALT lymphoma strain in vivo, using a transgenic mice mutagenesis assay to study the molecular mechanisms involved in the host response to the H. pylori infection, focusing on the influence of DNA repair systems on the genotoxicity associated to the H. Pylori infection

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